SINGLE MOLECULE IMAGING LAB (SMILe)
WELCOME TO SMILe !
A Single Molecule Imaging Lab
“You can observe a lot by just watching!” --Yogi Berra
Research & Discoveries
Single-molecule imaging is a powerful tool for the study of dynamic molecular interactions in biological and chemical systems.
Single-Molecule Imaging Probe
Synthetic Chemistry
Single molecule imaging probe suffers from photobleaching and non-manipulatable blinking. Our goal is developing super-photostable probes and manipulating their on-off state, offering new solutions for long-term single molecule tracking and super-resolution imaging based in single molecule localization. We are particularly interested in lanthanide based upconversion nanoprobes and stimulus-activatable organic dyes.
Single-Molecule Imaging System
Photonics
All the setups in our lab are home-built systems tailored to specific applications. For example, we are working on improving super-resolution imaging based on single molecule localization for better biocompatibility,
Investigating Biological And Chemical Mechanism
Application
The mitochondrion is a double membrane-bound organelle found in most eukaryotic organisms. Mitochondria generate most of the cell's supply of ATP, used as a source of chemical energy. Mitochondrion is thus termed the powerhouse of the cell. We are interested in using single molecule imaging and single molecule localization based super-resolution imaging to study the fusion, fission, and transport of mitochondrion in live neuron, as well as membrane associated bio-interface.
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Meet the Team
AVAILABLE POSITIONS
Current Opportunities at Single Molecule Imaging Lab (SMILe)
+86-21-31249196
Graduate Student Positions
We are currently recruiting graduate students. We welcome applications from all senior undergraduate students, and preference will be given to students who have research experience in our group.
Research Assistant and Postdoc Positions
Research Assistant and Postdoc positions are available in our group. We sponsor postdoc fellowships with internationally competitive salary and benefits for qualified candidates. We are particularly interested in recent PhD’s with a background in organic synthesis and neuron biology.
CONTACT US
Department of Chemistry, 2005 Songhu Road, Shanghai, CN